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Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
20.6K
Current and future applications of corneal cross-linking
Sumitra S Khandelwal1, J Bradley Randleman
1aBaylor College of Medicine, Cullen Eye Institute, Houston, Texas, USA bDepartment of Ophthalmology, Emory University cEmory Vision, Emory Eye Center, Atlanta, Georgia, USA.
Current Opinion in Ophthalmology
|March 19, 2015
Summary
Corneal cross-linking (CXL) is a safe and effective treatment for keratoconus and ectasia. Research is evolving, leading to new techniques and expanded applications for CXL in eye care.
Area of Science:
- Ophthalmology
- Corneal Science
- Biomaterials Science
Background:
- Keratoconus and corneal ectasia are progressive conditions leading to vision impairment.
- Infectious keratitis poses a significant threat to ocular health and vision.
- Corneal cross-linking (CXL) has emerged as a promising therapeutic approach.
Purpose of the Study:
- To review current concepts and future directions of corneal cross-linking (CXL).
- To evaluate CXL as a treatment for keratoconus, post-refractive surgery ectasia, and infectious keratitis.
Main Methods:
- Review of laboratory and clinical studies on corneal cross-linking.
- Analysis of new directions, indications, techniques, and protocols in CXL research.
Main Results:
- Established safety and success of CXL for keratoconus and corneal ectasias.
- Emerging studies explore new indications, compare techniques, and analyze novel protocols.
Conclusions:
- Bench and clinical research support modifications to standard CXL protocols.
- Expansion of CXL concepts includes accelerated CXL, epithelium-sparing approaches, and outcome measurement.
