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Updated: Apr 16, 2026
Author Spotlight: Fluorescence-Based Quantification of Mitochondrial Membrane Potential and Superoxide Levels Using Live Imaging in HeLa Cells
Published on: May 12, 2023
A ratiometric fluorescent probe for in situ quantification of basal mitochondrial hypochlorite in cancer cells
Ji-Ting Hou1, Kun Li, Jin Yang
1Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry Sichuan University, 29, Wangjiang Road, Chengdu, Sichuan Province, P. R. China. kli@scu.edu.cn xqyu@scu.edu.cn.
Abstract:
A ratiometric fluorescent probe () for ClO(-) based on the conjugate of coumarin-rhodamine was presented, which could sense ClO(-) with fast response (within 5 s), high sensitivity and excellent selectivity. More importantly, is the first mitochondria-targeted ratiometric fluorescent probe to image exogenous and endogenous ClO(-).
