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Published on: February 6, 2021
Sterile endophthalmitis after intravitreal ocriplasmin injection: report of a single case
1Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, Maryland.
Purpose:
To report a case of presumed sterile endophthalmitis after intravitreal ocriplasmin injection.
Methods:
Observational case report. Review of clinical examination, ocular imaging, and published literature.
Results:
A 67-year-old woman with early cataracts presented with decreased vision in the left eye related to vitreomacular adhesion. She was treated with intravitreal ocriplasmin injection and developed a severe anterior chamber inflammatory reaction in less than 24 hours after the injection. Inflammation responded completely to topical steroids alone, without topical or intravitreal antibiotics.
Conclusion:
Patients treated with intravitreal ocriplasmin may develop an acute inflammatory reaction, which can be severe.

