Midtrimester Isolated Short Femur Length as a Predictor of Adverse Pregnancy Outcome
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Published on: June 27, 2025
Amir Aviram1, Ron Bardin, Arnon Wiznitzer
1Helen Schneider Hospital for Women, Rabin Medical Center, Petah Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Objective:
The aim of this study was to investigate whether midtrimester isolated short femur length is associated with pregnancy complications.
Study Design:
Retrospective analysis of pregnancies with a midtrimester femur length <5th percentile for gestational age compared to controls with a femur length ≥5th percentile. Outcome measures included hypertensive disorders, being small for gestational age, oligohydramnios and preterm delivery.
Results:
2,105 women were eligible for this study, 85 (3.45%) of whom were in the study group and 2,020 were controls. Birth weight <10th percentile for gestational age (OR 4.4, 95% CI 2.5-7.8), birth weight <3rd percentile for gestational age (OR 31.0, 95% CI 13.3-72.3) and severe preeclampsia (OR 6.3, 95% CI 1.4-28.6) were significantly associated with midtrimester isolated short femur length.
Conclusions:
Midtrimester isolated short femur length is associated with higher rates of being small for gestational age and preeclampsia.
