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Dermatoglyphic patterns in cystic fibrosis children

Atefeh Ezzati1, Fereshteh Batoei2, Seyed-Ali Jafari3

  • 1Clinical Research Development Center, Ghaem Hospital.

Iranian Journal of Pediatrics
|March 21, 2015
PubMed

Insights

Fingerprint and palm patterns show significant differences in children with Cystic Fibrosis (CF). These dermatoglyphic characteristics may aid in the supplementary diagnosis of CF.

Area of Science:

  • Dermatoglyphics
  • Genetics
  • Pediatrics

Background:

  • Fingerprint and palm patterns are potentially genetically determined congenital abnormalities.
  • Cystic Fibrosis (CF) is a genetic disorder with potential dermatoglyphic manifestations.

Purpose of the Study:

  • To investigate differences in fingerprint and palm patterns between children with CF and healthy children.
  • To explore the potential of dermatoglyphics as a supplementary diagnostic tool for CF.

Main Methods:

  • Comparative analysis of dermatoglyphic features (fingerprint patterns, Total Ridge Count, a-b ridge count, atd angles) in 46 CF children and 341 healthy individuals.
  • Assessment of asymmetry and dissimilarity in dermatoglyphic traits between groups.
  • Statistical analysis including Chi-square, Mann-Whitney U test, and Fisher's exact test.

Main Results:

  • Significant differences observed in Total Ridge Count (TRC) for specific fingers and atd angles between CF and control groups.
  • Significant differences found in a-b ridge counts for both right and left hands.
  • No significant differences in asymmetry of atd angles, a-b ridge counts, or pattern dissimilarity scores.

Conclusions:

  • Dermatoglyphic characteristics exhibit significant variations in children with Cystic Fibrosis.
  • These findings suggest that dermatoglyphic patterns can serve as a supplementary diagnostic method for CF.
Abstract

Keywords:
ChildrenCystic FibrosisDermatglyphicsFingerprintsPalm Patterns

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