Dermatoglyphic patterns in cystic fibrosis children.

Area of Science:

• Dermatoglyphics
• Genetics
• Pediatrics

Background:

• Fingerprint and palm patterns are potentially genetically determined congenital abnormalities.
• Cystic Fibrosis (CF) is a genetic disorder with potential dermatoglyphic manifestations.

Purpose of the Study:

• To investigate differences in fingerprint and palm patterns between children with CF and healthy children.
• To explore the potential of dermatoglyphics as a supplementary diagnostic tool for CF.

Main Methods:

• Comparative analysis of dermatoglyphic features (fingerprint patterns, Total Ridge Count, a-b ridge count, atd angles) in 46 CF children and 341 healthy individuals.
• Assessment of asymmetry and dissimilarity in dermatoglyphic traits between groups.
• Statistical analysis including Chi-square, Mann-Whitney U test, and Fisher's exact test.

Main Results:

• Significant differences observed in Total Ridge Count (TRC) for specific fingers and atd angles between CF and control groups.
• Significant differences found in a-b ridge counts for both right and left hands.
• No significant differences in asymmetry of atd angles, a-b ridge counts, or pattern dissimilarity scores.

Conclusions:

• Dermatoglyphic characteristics exhibit significant variations in children with Cystic Fibrosis.
• These findings suggest that dermatoglyphic patterns can serve as a supplementary diagnostic method for CF.