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The Emerging Potential of the Apelin-APJ System in Heart Failure

Jonathan R Dalzell1, John P Rocchiccioli2, Robin A P Weir3

  • 1British Heart Foundation Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland; Scottish Advanced Heart Failure Unit, Golden Jubilee National Hospital, Glasgow, Scotland.

Journal of Cardiac Failure
|March 22, 2015
PubMed
Summary

The apelin-APJ system, a key heart regulator, is down-regulated in heart failure. Augmenting this pathway offers a promising therapeutic strategy for heart failure treatment.

Keywords:
APJApelinheart failureneurohormonepathophysiology

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