Anaphylactic hypersensitivity to mercurochrome (merbrominum).

Area of Science:

• Immunology
• Allergology
• Dermatology

Background:

• Anaphylactic shock is a severe, immediate allergic reaction.
• Antiseptics like Mercurochrome can trigger hypersensitivity reactions.
• Diagnosing antiseptic allergy requires specific immunological testing.

Purpose of the Study:

• To investigate immediate hypersensitivity to Mercurochrome.
• To confirm allergy in a patient with anaphylactic shock.
• To explore cross-reactivity among organic mercurial compounds.

Main Methods:

• Intradermal skin testing was performed.
• Passive transfer (Prausnitz-Küstner) tests were utilized.
• In vitro histamine release assays were conducted.

Main Results:

• Immediate hypersensitivity to Mercurochrome was demonstrated.
• The patient exhibited a positive reaction to Mercurochrome.
• Cross-reactivity was observed between different organic mercury compounds.

Conclusions:

• Mercurochrome can induce immediate hypersensitivity reactions.
• Diagnostic tests confirmed Mercurochrome allergy.
• Cross-reactivity suggests a broader sensitivity to organic mercurials.