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Suicidal ideation among patients with Behçet's syndrome
Caner Saygin1, Didem Uzunaslan1, Gulen Hatemi1
1Behçet's Syndrome Research Centre, Istanbul University, Istanbul, Turkey.
Clinical and Experimental Rheumatology
|March 24, 2015
Summary
Behçet's syndrome patients with major organ involvement report higher suicidal ideation. Key predictors include disease activity, quality of life, and depression, aiding early identification of at-risk individuals.
Area of Science:
- Rheumatology
- Psychiatry
- Clinical Medicine
Background:
- Behçet's syndrome (BS) is a multisystem inflammatory disease.
- Suicidal ideation is a significant concern in chronic illness populations.
Purpose of the Study:
- To determine the frequency of suicidal ideation in Behçet's syndrome patients.
- To identify factors associated with increased suicidal ideation in BS.
Main Methods:
- Cross-sectional study comparing BS patients, ankylosing spondylitis patients, and healthy controls.
- Assessment of suicidal ideation using a standard questionnaire.
- Linear regression analysis to identify predictive factors including clinical features, quality of life, and depression scores.
Main Results:
- Behçet's syndrome patients with major organ involvement showed higher suicidal thoughts (42%) than those with mucocutaneous involvement (35%) and controls.
- Active major organ involvement correlated with increased suicidal thoughts (25.5%) compared to mucocutaneous involvement (8.7%) and active AS (10%).
- Independent predictors included patient-reported joint pain, Behçet's disease quality of life (BDQoL), Beck depression inventory (BDI) scores, prior suicidal thoughts, neurologic involvement, and past prednisone use.
Conclusions:
- Behçet's syndrome patients, particularly those with active major organ involvement, experience elevated suicidal ideation.
- Identifying risk factors like depression and disease activity can help clinicians proactively manage suicidal thoughts in BS patients.
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