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Published on: October 14, 2021
Socioeconomic status in Behçet's syndrome
Tumay Ak1, Sabriye Güner2, Busra Albayrak3
1Department of Internal Medicine, Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Istanbul, Turkey.
Clinical and Experimental Rheumatology
|June 29, 2026
Summary
Behçet's syndrome patients exhibit the lowest socioeconomic status (SES) compared to other chronic inflammatory diseases and healthy individuals. Lower SES in Behçet's syndrome is linked to disease activity and employment status, suggesting a bidirectional relationship.
Area of Science:
- Rheumatology
- Immunology
- Public Health
Background:
- Socioeconomic status (SES) is a critical determinant of health outcomes.
- Chronic inflammatory diseases can significantly impact an individual's socioeconomic well-being.
- Understanding SES disparities in Behçet's syndrome (BS) is crucial for targeted interventions.
Purpose of the Study:
- To compare the socioeconomic status (SES) of patients with Behçet's syndrome (BS) against other chronic inflammatory diseases and healthy controls (HC).
- To identify clinical factors associated with lower SES in BS patients.
- To explore potential bidirectional relationships between SES and disease activity in BS.
Main Methods:
- Validated Turkish versions of the InCharge Financial Distress/Financial Well-being (IFDFW) and Socioeconomic Status Composite (SES-C) scales were administered to 506 BS patients, 144 ankylosing spondylitis (AS), 113 psoriatic arthritis (PsA), 140 inflammatory bowel disease (IBD), 94 multiple sclerosis (MS) patients, and 402 HC.
- SES-C was the primary outcome measure.
- Ordinal logistic regression was used to identify independent SES predictors.
Main Results:
- Behçet's syndrome patients reported the lowest mean SES-C scores, with 33.9% in the very low or low SES categories, higher than IBD (25.7%), PsA (20.4%), AS (16.0%), HC (15.7%), and MS (11.7%).
- BS and IBD were independently associated with lower SES, while MS was associated with higher SES.
- In BS patients, employment status and BDCAF score were independent predictors of lower SES, even in those without major organ involvement.
Conclusions:
- Behçet's syndrome patients exhibit significantly lower socioeconomic status compared to other chronic inflammatory diseases and healthy controls.
- The distinct SES associations in BS and MS suggest disease-specific environmental influences on pathogenesis.
- A bidirectional relationship between disease activity and lower SES in BS is indicated, with low SES potentially exacerbating disease and active disease leading to socioeconomic decline via work disability.
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