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Fluorescence-based Monitoring of PAD4 Activity via a Pro-fluorescence Substrate Analog
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[Advances of human epididymis protein 4 in lung cancer]
Qing Ma1, Qian Wang1, Diansheng Zhong1
1Department of Medical Oncology, The General Hospital of Tianjin Medical University, Tianjin 300052, China.
Zhongguo Fei AI Za Zhi = Chinese Journal of Lung Cancer
|March 25, 2015
Abstract:
Human epididymis 4 (HE4) belongs to whey acidic 4-disulfide center protein family. It has the characteristics of inhibiting trypsin and high expression in the serum or malignant pleural effusion of patients with lung cancer. Clinical data showed that it has certain relevance to the diagnosis and prognosis of lung cancer. HE4 may be a new indicator of clinical diagnosis and prognosis evaluation.
