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Updated: Apr 15, 2026
Technique of Conjunctival Biopsy and Direct Immunofluorescence for Diagnosing Mucous Membrane Pemphigoid
Published on: June 17, 2025
[Mucosal lymphomatoid papulosis: 2 cases]
L Benslama1, C V Andre2, F Charlotte3
1Service de stomatologie et chirurgie maxillo-faciale, AP-HP, DHU Fast, GH Pitié-Salpêtrière-Charles-Foix, 75013 Paris, France; UMR 8256 B2A, Sorbonne universités, UPMC université Paris 06, 75005 Paris, France.
Background:
Lymphomatoid Papulosis (LP) is a chronic dermatosis progressing by flare-up. According to the WHO-EORTC classification, LP is a form of CD30+ primitive cutaneous lympho-proliferation. Mucosal lesions are rare, with 15 published cases. We report two new cases of oral localizations, without any cutaneous involvement.
Patients And Methods:
Two women, 32 and 63 years old, presented with an isolated painful oral ulceration, of the maxillary tuberosity and of the inner side of the cheek respectively. The general state of health was preserved. Immunohistochimical analysis of the biopsies showed two Type A LPs. Lesions spontaneously resolved.
Discussion:
Among the rare published cases, oral localization involved exclusively the tongue and the labial mucosa and almost all patients presented with previous cutaneous lesions. Isolated maxillary tuberosity or cheek involvements were not described yet.
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