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Calcium-siRNA nanocomplexes: the importance of reversibility

Kinam Park1

  • 1Purdue University, Departments of Biomedical Engineering and Pharmaceutics, West Lafayette, IN 47907, USA.

Journal of Controlled Release : Official Journal of the Controlled Release Society
|March 25, 2015
PubMed
Abstract

No abstract available in PubMed .

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Calmodulin (CaM) is a calcium-binding protein in eukaryotes that controls various calcium-regulated cellular processes. It has four calcium-binding sites that bind calcium to form the calcium-calmodulin ( Ca2+-CaM) complex. GPCR stimulation increases the calcium levels in the cells that bind to CaM and induces a conformational change.
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