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Related Experiment Video

Updated: Apr 15, 2026

Collection, Expansion, and Differentiation of Primary Human Nasal Epithelial Cell Models for Quantification of Cilia Beat Frequency
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The nasal cycle and age.

Mark R Williams1, Ronald Eccles

  • 1Common Cold Centre, Cardiff School of Biosciences, Cardiff University , Cardiff, Wales , UK.

Acta Oto-Laryngologica
|March 25, 2015
PubMed
Summary
This summary is machine-generated.

The nasal cycle

Keywords:
Anterior rhinomanometryCNS diseaseagingautonomic nervous systemnasal airflowreciprocal changessympathetic control

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Area of Science:

  • Aging and Central Nervous System (CNS) Research
  • Respiratory Physiology
  • Nasal Airflow Dynamics

Background:

  • The nasal cycle, characterized by alternating congestion and decongestion of nasal cavities, is a physiological phenomenon.
  • Previous research suggests age-related changes may impact nasal cycle function.

Purpose of the Study:

  • To investigate the impact of aging on the reciprocal nature of the nasal cycle.
  • To assess if changes in the nasal cycle correlate with aging.

Main Methods:

  • Utilized anterior rhinomanometry to measure nasal airflow changes.
  • Assessed nasal airflow reciprocity in a single male subject at ages 28 and 66.

Main Results:

  • Demonstrated significant nasal cycle reciprocity at age 28 (correlation coefficients: -0.81, -0.83, -0.79).
  • Observed non-significant nasal cycle reciprocity at age 66 (correlation coefficients: 0.02, -0.43).

Conclusions:

  • The reciprocal nature of the nasal cycle significantly declined with advancing age.
  • Nasal cycle studies may serve as a potential indicator for central nervous system (CNS) disease and aging.