Cryptococcal osteomyelitis in an adolescent survivor of T-cell acute lymphoblastic leukemia
Djin-Ye Oh1, P Pallavi Madhusoodhan, Deborah J Springer
1From the *Saul Krugman Division of Pediatric Infectious Diseases, Department of Pediatrics, New York University Medical School, New York, NY; †Division of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA; ‡Division of Pediatric Hematology and Oncology, Department of Pediatrics, New York University Medical School, New York, NY; §Department of Molecular Genetics and Microbiology (MGM), ¶Department of Pharmacology and Cancer Biology, and ‖Department of Medicine, Duke University Medical Center, Durham, NC; **Department of Pathology, New York University Medical School, New York, NY; and ††Division of Pediatric Hematology and Oncology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT.
Abstract:
Cryptococcosis is infrequent in children, and isolated cryptococcal osteomyelitis is rarely encountered. Here, we describe a 14-year-old patient in remission from T-cell acute lymphoblastic leukemia with osteomyelitis because of Cryptococcus neoformans var. grubii. The patient was effectively treated with antifungal therapy.
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