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Twin-twin transfusion syndrome: neurodevelopmental screening test
Amabile Vessoni Arias1, Denise Campos1, Thatiane Moura Campos-Zanelli1
1Departamento de Neurologia, Centro de Investigação em Pediatria, Universidade Estadual de Campinas, Campinas, SP, Brazil.
Arquivos De Neuro-Psiquiatria
|March 26, 2015
Summary
Survivors of twin-twin transfusion syndrome (TTTS) generally show normal neurodevelopmental outcomes. However, preterm infants may have lower gross motor scores, warranting continued developmental monitoring.
Area of Science:
- Pediatric Neurology
- Neonatalogy
- Developmental Psychology
Background:
- Twin-twin transfusion syndrome (TTTS) is a serious complication in monochorionic pregnancies.
- Fetoscopic laser coagulation (FLC) is a common treatment for TTTS.
- Neurodevelopmental outcomes in TTTS survivors require thorough assessment.
Purpose of the Study:
- To evaluate the neurodevelopmental functions (cognition, language, motor skills) in survivors of TTTS.
- To identify potential developmental disparities among these children.
Main Methods:
- An observational, cross-sectional study was conducted.
- 67 monochorionic diamniotic twins treated with FLC for TTTS were assessed.
- Bayley Scales of Infant and Toddler Development Screening Test-III was used for evaluations ranging from 1 month to 2 years 4 months.
Main Results:
- The majority of TTTS survivors achieved competent neurodevelopmental levels.
- Preterm infants demonstrated significantly lower scores in the gross motor subtest compared to term infants (p = 0.036).
Conclusions:
- Most children treated for TTTS exhibit age-appropriate development.
- Children identified as at-risk require ongoing developmental surveillance throughout childhood.
