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1D NMR Homodecoupled (1)H Spectra with Scalar Coupling Constants from 2D NemoZS-DIAG Experiments
Axelle Cotte1, Damien Jeannerat
1Department of organic chemistry, University of Geneva, 30 Quai E. Ansermet, 1211 Geneva 4 (Switzerland).
Abstract:
A two-dimensional liquid-state NMR experiment cleanly separating chemical shifts and scalar couplings information is introduced. This DIAG experiment takes advantage of a drastic reduction of the spectral window in the indirect dimension to be quickly recorded and of a new non-equidistant modulation of the selective pulse to improve the sensitivity of the broadband homodecoupling Zangger-Sterk sequence element by one order of magnitude. A simple automatic analysis results in 1D spectra displaying singlets and lists of the scalar couplings for first-order multiplets. This facilitates the analysis of 1D spectra by resolving multiplets based on their differences in chemical shifts and coupling structures.
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