History and evolution of cytogenetics

Malcolm A Ferguson-Smith1

  • 1Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 0ES UK.

Molecular Cytogenetics
|March 27, 2015
PubMed
Summary

Cytogenetics has evolved with technological advancements, focusing on chromosome structure and function. Future research in molecular cytogenetics requires a deeper understanding of these fundamental aspects.

Related Concept Videos

Karyotyping01:17

Karyotyping

Overview
70.7K
Karyotyping01:17

Karyotyping

12.1K
Polytene Chromosomes02:04

Polytene Chromosomes

Polytene chromosomes are giant interphase chromosomes with several DNA strands placed side by side. They were discovered in the year 1881 by Balbiani in salivary glands, intestine, muscles, malpighian tubules, and hypoderm of larvae Chironomus plumosus. Hence, these are also called "Salivary gland chromosomes." These are found in insects of the order Diptera and Collembola; in certain organs of mammals; and synergids, antipodes of flowering plants. Polytene chromosomes are also...
11.4K
Polytene Chromosomes02:04

Polytene Chromosomes

3.7K
Synteny and Evolution02:31

Synteny and Evolution

John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
4.0K
Chromosomal Theory of Inheritance01:39

Chromosomal Theory of Inheritance

In 1866, Gregor Mendel published the results of his pea plant breeding experiments, providing evidence for predictable patterns in the inheritance of physical characteristics. The significance of his findings was not immediately recognized. In fact, the existence of genes was unknown at the time. Mendel referred to hereditary units as “factors.”
61.6K