Related Experiment Video
Updated: Apr 15, 2026

Implementation of a Coherent Anti-Stokes Raman Scattering CARS System on a Ti:Sapphire and OPO Laser Based Standard Laser Scanning Microscope
Published on: July 17, 2016
Applications of coherent Raman scattering microscopies to clinical and biological studies
Iwan W Schie1, Christoph Krafft, Jürgen Popp
1Leibniz Institute of Photonic Technology, Albert-Einstein-Straße 9, 07745 Jena, Germany. christoph.krafft@ipht-jena.de.
Abstract:
Coherent anti-Stokes Raman scattering (CARS) microscopy and stimulated Raman scattering (SRS) microscopy are two nonlinear optical imaging modalities that are at the frontier of label-free and chemical specific biological and clinical diagnostics. The applications of coherent Raman scattering (CRS) microscopies are multifold, ranging from investigation of basic aspects of cell biology to the label-free detection of pathologies. This review summarizes recent progress of biological and clinical applications of CRS between 2008 and 2014, covering applications such as lipid droplet research, single cell analysis, tissue imaging and multiphoton histopathology of atherosclerosis, myelin sheaths, skin, hair, pharmaceutics, and cancer and surgical margin detection.
More Related Videos
Related Concept Videos
Raman Spectroscopy: Overview
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
Raman Spectroscopy Instrumentation: Overview
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
Applications Of NMR In Biology
Imaging Biological Samples with Optical Microscopy
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
X-ray Diffraction of Biological Samples
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are scattered by the electron clouds around the sample atoms. The X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal...
Applications of IR Spectroscopy: Overview

