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Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action

Olivier René1, Benjamin P Fauber1, Gladys de Leon Boenig1

  • 1Genentech, Inc., 1 DNA Way, South San Francisco, California 94080, United States.

ACS Medicinal Chemistry Letters
|March 28, 2015
PubMed

Keywords:
IL-17PBMCRORcRORγTH17agonistinverse agonist

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