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Multiple jaw cysts-unveiling the Gorlin-Goltz syndrome
S Manjima1, Zameera Naik1, Vaishali Keluskar1
1Department of Oral Medicine and Radiology, KLE VKIDS, Belgaum, Karnataka Belgaum, India.
Contemporary Clinical Dentistry
|March 31, 2015
Summary
Gorlin-Goltz syndrome, a rare condition, involves basal cell nevi and jaw cysts. Early dental diagnosis is crucial for managing this genetic disorder and preventing complications.
Area of Science:
- Oral Medicine
- Genetics
- Dermatology
Background:
- Gorlin-Goltz syndrome (GGS), also known as basal cell nevus syndrome, is a rare autosomal dominant disorder.
- It is characterized by a triad of basal cell carcinomas, odontogenic keratocysts, and skeletal anomalies, including bifid ribs and calcified falx cerebri.
Observation:
- Dentists play a critical role in early GGS diagnosis due to its significant oral and maxillofacial manifestations.
- Odontogenic keratocysts in GGS patients are often multiple, extensive, and can lead to jaw deformities and facial disfigurement.
Findings:
- This case report details a 16-year-old patient presenting with multiple odontogenic cysts.
- Subsequent investigations confirmed the diagnosis of Gorlin-Goltz syndrome.
Implications:
- Early and accurate diagnosis of GGS through dental examination is essential for timely intervention.
- Proactive management can significantly reduce the morbidity associated with GGS, including the risk of basal cell carcinomas and severe facial disfigurement.
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