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Updated: Apr 15, 2026

Noninvasive Electrocardiography in the Perinatal Mouse
Published on: June 12, 2020
Drug resistant fetal arrhythmia in obstetric cholestasis
Nahide Altug1, Ayse Kirbas2, Korkut Daglar2
1Department of Pediatric Cardiology, Zekai Tahir Burak Women's Health Education and Research Hospital, 06680 Cankaya, Ankara, Turkey.
Abstract:
Obstetric cholestasis (OC) is a pregnancy specific liver disease characterized by increased levels of bile acid (BA) and pruritus. Raised maternal BA levels could be associated with intrauterine death, fetal distress, and preterm labor and also alter the rate and rhythm of cardiomyocyte contraction and may cause fetal arrhythmic events. We report a case of drug resistant fetal supraventricular tachycardia and concomitant OC. Conclusion. If there are maternal OC and concomitant fetal arrhythmia, possibility of the resistance to antiarrhythmic treatment should be kept in mind.
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