Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Lipid-derived Compounds in the Human Body01:31

Lipid-derived Compounds in the Human Body

7.5K
Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various  biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
7.5K
Inflammation01:38

Inflammation

65.5K
Overview
65.5K
Inflammatory Response01:28

Inflammatory Response

19.7K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
19.7K
Lipid-Lowering Drugs: Statins and Miscellaneous Agents01:20

Lipid-Lowering Drugs: Statins and Miscellaneous Agents

1.9K
Hyperlipidemia, a medical condition often referred to as high cholesterol, is characterized by abnormally elevated levels of lipids in the bloodstream. When present in excess, these lipids, specifically cholesterol and triglycerides, can lead to serious health complications, often involving cardiovascular diseases. Illnesses like atherosclerosis, heart attacks, and pancreatitis have all been linked to untreated hyperlipidemia. This means controlling and regulating cholesterol and triglyceride...
1.9K
Inflammatory Response II: Inflammatory Exudate and Tissue Repair01:24

Inflammatory Response II: Inflammatory Exudate and Tissue Repair

9.6K
The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
9.6K
T Cell Types and Functions01:24

T Cell Types and Functions

3.5K
When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
3.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Socioeconomic status in Behçet's syndrome.

Clinical and experimental rheumatology·2026
Same author

The Therapeutic Potential of Intravenous Exosomes in the Treatment of Psoriasis.

International journal of dermatology·2026
Same author

Foreign body granuloma following leech therapy in hidradenitis suppurativa: A case complicated by lymphedema.

Dermatology online journal·2026
Same author

Beyond Aesthetics: Imaging-Based Evaluation of Carboxytherapy in Periorbital Hyperpigmentation.

Journal of clinical medicine·2026
Same author

Clinical and Demographic Features of Behçet's Disease: A Retrospective Analysis of 4007 Patients from a Single Center in Turkey.

Clinical and experimental dermatology·2026
Same author

Predictors of early high-level response to bimekizumab in patients with moderate-to-severe plaque psoriasis: a real-world cohort study.

Anais brasileiros de dermatologia·2026

Related Experiment Video

Updated: Apr 15, 2026

Shotgun Lipidomics of Rodent Tissues
11:46

Shotgun Lipidomics of Rodent Tissues

Published on: November 18, 2022

2.9K

Cutaneous inflammatory lipid mediators.

Zekayi Kutlubay, Yalçin Tüzün, Ronni Wolf

    Skinmed
    |April 1, 2015
    PubMed
    Summary

    Lipid mediators are crucial in skin inflammation, regulating physiological and pathological processes. Future therapies may target these mediators for novel anti-inflammatory treatments.

    Area of Science:

    • Dermatology
    • Immunology
    • Biochemistry

    Background:

    • Inflammation is a key physiological response to stimuli like infection or trauma.
    • Lipid mediators act as local regulators within skin's intercellular microenvironments.
    • These mediators are produced by all human tissues, with varying enzyme content.

    Purpose of the Study:

    • To highlight the significant effects and roles of lipid mediators in skin inflammation.
    • To focus on recent evidence from published studies regarding lipid mediators in skin.
    • To explore potential future therapeutic strategies involving lipid mediators.

    Main Methods:

    • Review of recent scientific literature on lipid mediators and skin inflammation.
    • Analysis of studies focusing on the biochemical pathways and functions of lipid mediators.

    More Related Videos

    Methods to Study Lipid Alterations in Neutrophils and the Subsequent Formation of Neutrophil Extracellular Traps
    10:58

    Methods to Study Lipid Alterations in Neutrophils and the Subsequent Formation of Neutrophil Extracellular Traps

    Published on: March 29, 2017

    10.1K

    Related Experiment Videos

    Last Updated: Apr 15, 2026

    Shotgun Lipidomics of Rodent Tissues
    11:46

    Shotgun Lipidomics of Rodent Tissues

    Published on: November 18, 2022

    2.9K
    Methods to Study Lipid Alterations in Neutrophils and the Subsequent Formation of Neutrophil Extracellular Traps
    10:58

    Methods to Study Lipid Alterations in Neutrophils and the Subsequent Formation of Neutrophil Extracellular Traps

    Published on: March 29, 2017

    10.1K
  • Synthesis of evidence regarding the impact of lipid mediators on inflammatory processes.

    • Main Results:

    • Lipid mediators play a major role in the complex processes of skin inflammation.
    • Recent studies provide substantial evidence for the involvement of lipid mediators.
    • Variations in enzyme content across tissues influence lipid mediator production and profiles.

    Conclusions:

    • Lipid mediators are central to the regulation of skin inflammation.
    • Pharmacological targeting of lipid mediators and their receptors presents a promising future approach.
    • Novel anti-inflammatory strategies may emerge from manipulating these lipid pathways.