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PRP as a New Approach to Prevent Infection: Preparation and In vitro Antimicrobial Properties of PRP
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[Research progress of preparation and components of platelet rich plasma]
Objective:
To review the research progress of the preparation and components of the platelet rich plasma (PRP).
Methods:
The recent literature concerning the biological mechanism, preparation, and components of PRP was analyzed and summarized.
Results:
The biological function of PRP depends on a series of intricate cascade of cellular and molecular events. PRP contains different concentrations of platelets, which would release a large number of the activated molecules, and also contains a small amount of white blood cells and red blood cells. The preparation of PRP is based on platelet concentration. Different preparation techniques would lead to different platelet concentrations, recovery ratios, and components.
Conclusion:
There is no uniform standard for the preparation of PRP. Different preparation methods and technical parameters of PRP will get different components and different concentrations of PRP, which also provide a reference for clinicians to select the most appropriate PRP for individual patient.
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