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Related Experiment Video

Updated: Apr 15, 2026

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Tips to diagnose uncommon nail disorders.

Samantha L Schneider1, Antonella Tosti2

  • 1Department of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami, Miami, 1600 Northwest 10th Avenue, FL 33136, USA; Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

Dermatologic Clinics
|April 2, 2015
PubMed
Summary

This review highlights six common and uncommon nail disorders frequently misdiagnosed by medical professionals. It emphasizes key diagnostic clues for conditions like onychomatricoma, Darier disease, and yellow nail syndrome.

Keywords:
Arrested nail growthDarier diseaseLichen striatusMelanonychiaNail patella syndromeOnychopapillomaTriangular lunulaYellow nail syndrome

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Area of Science:

  • Dermatology
  • Nail Medicine

Background:

  • Nail disorders are common but often misdiagnosed.
  • Accurate diagnosis is crucial for effective treatment and patient management.

Purpose of the Study:

  • To review six specific nail disorders that are frequently misdiagnosed.
  • To emphasize diagnostic clues for correct identification by clinicians.

Main Methods:

  • Review of literature and clinical features of selected nail disorders.
  • Focus on diagnostic criteria and differentiating features.

Main Results:

  • Detailed discussion of two common tumors: onychomatricoma and onychopapilloma.
  • Description of two rare genetic conditions: Darier disease and nail patella syndrome.
  • Explanation of two uncommon acquired disorders: yellow nail syndrome and lichen striatus.

Conclusions:

  • Familiarity with specific diagnostic clues can improve the accuracy of nail disorder diagnosis.
  • Correct diagnosis of these six conditions is achievable with careful clinical examination.