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Updated: Sep 27, 2026
Skin Punch Biopsy Explant Culture for Derivation of Primary Human Fibroblasts
Published on: July 7, 2013
Best way to perform a punch biopsy
Judith Domínguez-Cherit1, Daniela Gutiérrez Mendoza2
1Department of Dermatology, Insituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubiran", Av. Vasco de Quiroga #15, Colonia Belisario Dominguez Sección XVI, Delegación Tlalpan, CP 14000, México Distrito Federal 14000, Mexico.
Abstract:
Nail punch biopsy is used to obtain a tissue sample for the diagnosis and treatment of nail diseases. The best results will be possible if the surgeon is familiar with the anatomy and physiology of the nail apparatus. A punch biopsy can be used in all regions of the nail apparatus in the presence or absence of nail plate. When the procedure is performed with a careful handling of the anatomic site and specimen, in most cases a successful diagnosis can be achieved.
