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Influenza virus infections in the tropics during the first year of life

Daniel H Libraty1, Lei Zhang2, Mercydina Caponpon3

  • 1Division of Infectious Diseases, Department of Medicine, University of Massachusetts Medical School, Worcester, USA 01655 daniel.libraty@umassmed.edu.

Journal of Tropical Pediatrics
|April 2, 2015
PubMed

Insights

Influenza virus infections are common in infants with acute febrile illness in the Philippines tropics. This study found 31% of infants had influenza, often influenza A, during their first year of life.

Area of Science:

  • Tropical Medicine
  • Pediatric Infectious Diseases
  • Virology

Background:

  • Pediatric influenza virus infections in tropical regions, especially during infancy, remain under-documented.
  • This study investigated influenza virus infections in infants presenting with acute undifferentiated febrile illnesses in San Pablo, Laguna, Philippines.

Discussion:

  • Influenza virus was identified in 31% of infants with non-dengue acute undifferentiated febrile illnesses.
  • The majority of identified influenza cases were influenza A virus infections.
  • Most influenza cases were managed as outpatient cases.

Key Insights:

  • Influenza is a significant cause of non-dengue acute undifferentiated febrile illnesses in infants in tropical climates.
  • The median age of infected infants was 11.1 months.
  • Influenza cases showed a seasonal clustering between June and December.

Outlook:

  • Further research is needed to understand the full impact of influenza on infant health in tropical regions.
  • Enhanced surveillance for pediatric influenza in the tropics is recommended.
  • Understanding seasonal patterns can aid in timely diagnosis and management of infant febrile illnesses.

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