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Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
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Lung cancer.

Tim Akhurst1, Michael MacManus2, Rodney J Hicks1

  • 1Division of Radiation Oncology and Cancer Imaging, Centre for Molecular Imaging, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia; The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, Victoria, Australia.

PET Clinics
|April 2, 2015
PubMed
Summary
This summary is machine-generated.

(18)F-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) is crucial for diagnosing lung nodules and staging lung cancer. FDG-avid nodules require further evaluation, while non-avid ones can often be observed.

Keywords:
CT scanningChemotherapyLung cancerPositron emission tomographyRadiotherapy

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Area of Science:

  • Nuclear Medicine
  • Radiology
  • Oncology

Background:

  • Undiagnosed lung nodules require accurate characterization.
  • Primary lung cancer diagnosis and staging are critical for treatment planning.

Purpose of the Study:

  • To outline the role of FDG-PET/CT in evaluating lung nodules.
  • To emphasize its importance in lung cancer staging for curative therapy.

Main Methods:

  • Utilizes (18)F-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT).
  • Assesses FDG uptake in lung lesions for diagnostic and staging purposes.

Main Results:

  • FDG-PET/CT aids in evaluating undiagnosed lung nodules.
  • FDG-avid nodules necessitate further investigation, while non-avid nodules may be safely observed.
  • It serves as a primary staging tool for lung cancer patients considered for curative surgery or radiation therapy.

Conclusions:

  • FDG-PET/CT is a key imaging modality for lung nodules and lung cancer.
  • Its findings guide the need for further evaluation and treatment decisions.