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Updated: Aug 13, 2026

Functional Imaging of Brown Fat in Mice with 18F-FDG micro-PET/CT
Published on: November 23, 2012
Fluorodeoxyglucose PET/Computed Tomography in Multimodality and Theranostic Workflows
Yogita Khandelwal1, Komal Bishnoi1, Bela Jain1
1Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, 110029, India.
Abstract:
Theranostics, the integration of diagnostic imaging and targeted radionuclide therapy, has transformed oncological practice. While receptor-targeted tracers such as somatostatin receptor PET/computed tomography (CT) and prostate-specific membrane antigen PET/CT anchor most theranostic workflows, 18F-fluorodeoxyglucose (FDG) PET/CT retains an indispensable role across the spectrum of theranostic diseases. FDG PET images glucose metabolism and thereby captures biological information that receptor-targeted tracers cannot. This review synthesizes current evidence, guideline recommendations, and emerging applications, including total-body PET, AI-assisted quantification, radiomics, and novel fibroblast activation protein inhibitor targeted theranostics, to define the evolving position of FDG-PET/CT as a gatekeeper in the theranostic oncological workflow.
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