Large-volume barium aspiration
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Updated: Oct 12, 2026

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Published on: November 10, 2014
Gregory L Hundemer1, Varun Kumar1, Muthiah Vaduganathan1
1Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (Hundemer, Vaduganathan), and the Department of Medicine, Baylor College of Medicine, Houston, Texas (Kumar).
Abstract:
We present a case of large-volume barium aspiration in a 56-year-old woman with stage IV tongue squamous cell carcinoma and longstanding dysphagia. The patient rapidly developed hypoxemic respiratory failure from the resultant chemical pneumonitis. However, her respiratory status improved with supportive care alone in 48 hours. Barium aspiration is rare and often produces dramatic radiographic findings, but is generally associated with a favorable prognosis.
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