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Combat-Related Pythium aphanidermatum Invasive Wound Infection: Case Report and Discussion of Utility of Molecular
Aaron R Farmer1, Clinton K Murray2, Ian R Driscoll3
1San Antonio Military Medical Center, JBSA Fort Sam Houston, Texas, USA Aaron.r.farmer.mil@mail.mil.
Journal of Clinical Microbiology
|April 3, 2015
Abstract:
We describe a 22-year-old soldier with 19% total body surface area burns, polytrauma, and sequence- and culture-confirmed Pythium aphanidermatum wound infection. Antemortem histopathology suggested disseminated Pythium infection, including brain involvement; however, postmortem PCR revealed Cunninghamella elegans, Lichtheimia corymbifera, and Saksenaea vasiformis coinfection. The utility of molecular diagnostics in invasive fungal infections is discussed.

