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Updated: Apr 15, 2026

Physiology Lab Demonstration: Glomerular Filtration Rate in a Rat
Published on: July 26, 2015
Stability of renal function in spite of low glomerular filtration rate: a case report
Mohammad Reza Tamadon1, Seyed Seifollah Beladi Mousavi2
1Department of Internal Medicine, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, IR Iran.
Insights
Stable chronic kidney disease (CKD) management is achievable. Blood pressure control and standard treatments can maintain stage 4 CKD for years without progression, as seen in a 78-year-old patient.
Area of Science:
- Nephrology
- Internal Medicine
- Geriatrics
Background:
- Chronic kidney disease (CKD) is a progressive, irreversible decline in kidney function.
- CKD encompasses stages from proteinuria to chronic renal failure (CRF).
Introduction:
Chronic renal dysfunction is a progressive and irreversible process in kidney function, which often resulted in chronic kidney disease (CKD) or chronic renal failure (CRF). Range of CKD is varying from proteinuria and renal failure to CRF.
Case Presentation:
A 78-year-old man presented with stage 4 CKD for 7 years; the glomerular filtration rate (GFR) and creatinine levels remained constant despite no change in his weight.
Conclusions:
Although our patient had CKD stage 4, but his condition has not deteriorated and remained constant and stable for several years only by control of blood pressure and usual treatment which prescribed for patients at this stage.
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