[Configuration of corneal incisions with the excimer laser: an experimental study]

The potential applications of an ophthalmic excimer laser at 193 nm include its use as a precise trephine in keratoplasty procedures. In a series of 20 human autopsy and 40 pig cadaver eyes the histological and ultrastructural results of donor and recipient trephination and full-thickness corneal grafting using new mask systems were evaluated. In comparison with other beam delivery systems the "open mask system" allows the performance of excimer laser trephinations with reproducible wound configuration and geometry, with easy handling and high reliability. This technique enables the surgeon to surmount the mechanical limitations of cutting direction and makes non-circular trephinations possible.