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Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Height, weight and body mass index in adults with congenital heart disease
Camilla Sandberg1, Daniel Rinnström2, Mikael Dellborg3
1Heart Centre and Department of Public Health and Clinical Medicine, Umeå University, Sweden; Department of Community Medicine and Rehabilitation, Physiotherapy, Umeå University, Sweden.
Insights
Men with congenital heart disease (CHD) generally have lower BMI, with higher underweight prevalence, compared to controls. Women with CHD showed fewer differences, though complexity impacted men's height.
Area of Science:
- Cardiology
- Public Health
- Genetics
Background:
- High BMI is a known cardiovascular disease risk factor.
- Low BMI is associated with poorer outcomes in heart failure patients.
- Limited data exists on BMI distribution in adults with congenital heart disease (CHD).
Purpose of the Study:
- To investigate Body Mass Index (BMI) distribution across different BMI classes in adults with CHD.
- To compare BMI and height in adults with CHD to a reference population.
- To explore potential gender and CHD complexity-related differences.
Main Methods:
- Data from 2424 adult CHD patients from the Swedish Registry on Congenital Heart Disease.
- Comparison with a reference population (n=4605).
- Analysis of BMI (underweight, overweight, obesity) and height based on CHD type and gender.
Main Results:
- Men with CHD, particularly those with complex lesions like Fontan procedure, pulmonary atresia/double outlet right ventricle, and aortic valve disease, had lower prevalence of overweight/obesity compared to controls.
- Underweight (BMI < 18.5) was more common in men with CHD (complex and simple lesions).
- Overt obesity (BMI ≥ 30) was more prevalent in women with aortic valve disease. Men with complex CHD were shorter than controls, unlike women.
Conclusions:
- Men with CHD generally exhibit lower BMI, characterized by higher underweight rates and lower overweight/obesity rates in certain complex conditions, compared to the general population.
- Limited BMI differences were observed between women with CHD and controls.
- CHD complexity significantly impacted height in men, with unknown causes and prognostic implications for these gender-specific findings.
Background:
High BMI is a risk factor for cardiovascular disease and, in contrast, low BMI is associated with worse prognosis in heart failure. The knowledge on BMI and the distribution in different BMI-classes in adults with congenital heart disease (CHD) are limited.
Methods And Results:
Data on 2424 adult patients was extracted from the Swedish Registry on Congenital Heart Disease and compared to a reference population (n=4605). The prevalence of overweight/obesity (BMI ≥ 25) was lower in men with variants of the Fontan procedure, pulmonary atresia (PA)/double outlet right ventricle (DORV) and aortic valve disease (AVD) (Fontan 22.0% and PA/DORV 15.1% vs. 43.0%, p=0.048 and p<0.001) (AVD 37.5% vs. 49.3%, p<0.001). Overt obesity (BMI ≥ 30) was only more common in women with AVD (12.8% vs. 9.0%, p=0.005). Underweight (BMI<18.5) was generally more common in men with CHD (complex lesions 4.9% vs. 0.9%, p<0.001 and simple lesions 3.2% vs. 0.6%, <0.001). Men with complex lesions were shorter than controls in contrast to females that in general did not differ from controls.
Conclusion:
Higher prevalence of underweight in men with CHD combined with a lower prevalence of overweight/obesity in men with some complex lesions indicates that men with CHD in general has lower BMI compared to controls. In women, only limited differences between those with CHD and the controls were found. The complexity of the CHD had larger impact on height in men. The cause of these gender differences as well as possible significance for prognosis is unknown.
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