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Updated: Apr 15, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Evidence-informed healthcare through integration of health research
Rebecca O Barnes1, B J Holmes2, R Lindstrom3
1Research and Capacity Building, Vancouver Island Health Authority, Victoria, British Columbia, Canada. rebecca.barnes@viha.ca.
Abstract:
A foundational element of modern healthcare is an evidence-based practice. However, the conduct of research to generate evidence and the subsequent application of research findings are viewed by many Canadian healthcare organizations as separate from healthcare delivery. This mindset impedes effective translation of knowledge into practice. In this article, underlying issues that enable this disintegrated model to persist are described, and strategies to help healthcare organizations achieve integration of research are summarized.
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