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Dissecting Innate Immune Signaling in Viral Evasion of Cytokine Production
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γHV68 vGAT: a viral pseudoenzyme pimping for PAMPs
Daniel Kolakofsky1, Dominique Garcin1
1Department of Microbiology and Molecular Medicine, University of Geneva, 1211 Geneva 4, Switzerland.
Molecular Cell
|April 4, 2015
Abstract:
In this issue, He et al. (2015) show how herpes virus usurps a cellular metabolic enzyme to induce RIG-I deamidation and RNA-independent activation, likely to better prevent further innate immune responses.

