May-Thurner syndrome: correlation between digital subtraction and computed tomography venography

Area of Science:

• Vascular Imaging
• Diagnostic Radiology
• Venous Disease Evaluation

Background:

• May-Thurner syndrome diagnosis relies on Digital Subtraction Venography (DSV) and Computed Tomography Venography (CTV).
• Limited data exists on the correlation between these two imaging modalities for May-Thurner syndrome.
• This study investigates the relationship between DSV and CTV findings in May-Thurner syndrome patients.

Purpose of the Study:

• To assess the correlation between Digital Subtraction Venography (DSV) and Computed Tomography Venography (CTV) in diagnosing May-Thurner syndrome.
• To compare hemodynamic parameters from DSV with anatomical measurements from CTV.
• To establish the relationship between imaging findings and the underlying pathophysiology of May-Thurner syndrome.

Main Methods:

• Retrospective case-series study of 42 patients diagnosed with May-Thurner syndrome.
• Patients underwent both DSV (evaluating reflux, start-up time, flow time) and CTV (calculating cross-sectional area and diameter ratios).
• Spearman's rank correlation coefficients were used to analyze the relationship between DSV and CTV variables.

Main Results:

• Reflux was graded using DSV, with Grades II and III being most common (28.6% and 40.5%).
• Mean reflux start-up time in DSV showed a positive correlation with CTV's cross-sectional area ratio (r=0.518, p=0.002) and diameter ratio (r=0.413, p=0.019).
• CTV anatomical ratios correlated significantly with DSV hemodynamic measurements.

Conclusions:

• CTV's anatomical measurements (area and diameter ratios) correlate with DSV's reflux start-up time in May-Thurner syndrome.
• Both CTV and DSV provide crucial diagnostic and evaluative information for May-Thurner syndrome.
• The observed correlation supports the understanding of May-Thurner syndrome's pathophysiology, linking anatomical and hemodynamic factors.