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The Philadelphia Neurodevelopmental Cohort: A publicly available resource for the study of normal and abnormal brain

Theodore D Satterthwaite1, John J Connolly2, Kosha Ruparel1

  • 1Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

Neuroimage
|April 4, 2015
PubMed

Insights

The Philadelphia Neurodevelopmental Cohort (PNC) offers valuable neuroimaging, clinical, and genomic data for child development research. This rich dataset is now accessible via the Database of Genotypes and Phenotypes (dbGaP) for neuroscience studies.

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Genetics

Background:

  • The Philadelphia Neurodevelopmental Cohort (PNC) is a large-scale study.
  • It investigates child development using neuroimaging, clinical, and genomic data.

Purpose of the Study:

  • To announce the public availability of PNC data.
  • To guide users on accessing this neurodevelopmental resource via dbGaP.

Main Methods:

  • Data aggregation from the PNC study.
  • Data deposition into the Database of Genotypes and Phenotypes (dbGaP).

Main Results:

  • PNC data, including neuroimaging, phenotypes, and genomics, is now publicly accessible.
  • This resource facilitates research into normal and abnormal neurodevelopment.

Conclusions:

  • The publicly available PNC data via dbGaP is a significant resource.
  • It supports the broader neuroscience community in studying neurodevelopment.

Keywords:
AdolescenceData-sharingDevelopmentMRINeuroimaging

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