Related Experiment Video
Updated: Apr 15, 2026

An In Vitro Batch-culture Model to Estimate the Effects of Interventional Regimens on Human Fecal Microbiota
Published on: July 31, 2019
Fate, activity, and impact of ingested bacteria within the human gut microbiota
Muriel Derrien1, Johan E T van Hylckama Vlieg1
1Danone Nutricia Research, RD 128 Avenue de la Vauve, 91767 Palaiseau, France.
Abstract:
The human gut contains a highly diverse microbial community that is essentially an open ecosystem, despite being deeply embedded within the human body. Food-associated fermentative bacteria, including probiotics, are major sources of ingested bacteria that may temporarily complement resident microbial communities, thus forming part of our transient microbiome. Here, we review data on the fate and activity of ingested bacteria and, in particular, lactobacilli and bifidobacteria in the gastrointestinal (GI) tract and their impact on the composition and metabolism of the gut microbiome with a focus on data from clinical studies. In addition, we discuss the mechanisms involved and the potential impact on the host's health.
More Related Videos
Related Concept Videos
Introduction to the Human Microbiota
Functions of the Gut Microbiota
Microbiota of the Stomach and Small Intestine
Bacterial Flora of the Large Intestine
The normal gut flora of the colon plays a critical role in generating essential vitamins such as vitamins K, B5, and B7.
Microbiota of the Large Intestine
Probiotics

