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Updated: Apr 15, 2026

Diagnosis of Neoplasia in Barrett’s Esophagus using Vital-dye Enhanced Fluorescence Imaging
Published on: May 11, 2014
[Morphological changes of the esophagus in adenocarcinoma and squamous cell carcinoma]
Purpose:
To study the micro-topography of the abdominal wall of the esophagus and give it a quantitative characterization of tumor pathology of the esophagus.
Methods:
The study was performed using morphological methods: 1 anatomical dissection; 2 gistotopographical method with coloring of gistotopogramms with hematoxylin-eosin and Van Gieson; 3 Morphometry of macro and microstructures of the esophagus. Operating studied material from 15 patients who over the tumor lesion was performed resection of the lower third of the esophagus and the upper part of the stomach. Operations were carried out on the basis of the thoracic department of the Orenburg Regional Clinical Oncology Center (ORCOC).
Results:
This article describes the features of the morphological changes in the abdominal wall of the esophagus at its two forms of tumor lesions: in squamous cell carcinoma and in adenocarcinoma. For adenocarcinoma and squamous cell carcinoma is characterized by a different type of growth, a different degree of sprouting layers of the esophageal wall, different propensity to metastasize within the wall of the esophagus. Submucosa of the esophagus is the main layer in which there are significant changes in neoplastic lesions of the esophagus, both within tumor and in adjacent areas of the esophageal wall.
Conclusion:
The common involvement of submucosa of the abdominal esophagus in the pathological process in its malignant lesions (up to 5 cm in our study) should be considered when determining the upper limit of esophageal resection.
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