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Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
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Synthesis and Regulation of Thyroid Hormones01:20

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
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The Parathyroid Glands00:59

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The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
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Functions of Thyroid Hormones01:18

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The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
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Updated: Apr 15, 2026

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Parvovirus and thyroid cancer.

Jacqueline A Hobbs1, Laura A Adamson-Small1

  • 1Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL.

Seminars in Oncology
|April 7, 2015
PubMed
Summary
This summary is machine-generated.

Human parvovirus B19 (EVB19) DNA, RNA, and protein are found in thyroid tissues, suggesting a potential indirect role in thyroid cancer. Further research is needed to confirm this link.

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Area of Science:

  • Virology
  • Oncology
  • Endocrinology

Background:

  • Parvoviruses are small DNA viruses with diverse pathogenic potential.
  • An emerging interest links parvoviruses to thyroid diseases.
  • This review focuses on parvoviruses and thyroid cancer specifically.

Purpose of the Study:

  • To review and evaluate evidence on parvoviruses in thyroid cancer.
  • To explore the association between human erythrovirus B19 (EVB19) and thyroid cancer.
  • To discuss potential indirect roles of EVB19 in thyroid cancer pathogenesis.

Main Methods:

  • Literature review and evidence appraisal.
  • Analysis of studies investigating parvovirus presence in thyroid tissues.
  • Examination of EVB19 DNA, RNA, and protein expression in thyroid cancer.

Main Results:

  • Limited direct evidence links animal parvoviruses to thyroid cancer.
  • Growing evidence suggests an association between EVB19 and thyroid cancer.
  • EVB19 genetic material and proteins are detected in various thyroid tissues.

Conclusions:

  • A direct causative role for EVB19 in thyroid cancer is not yet established.
  • An indirect role for EVB19 in thyroid cancer pathogenesis is hypothesized.
  • More research is required to elucidate the precise role of EVB19 in thyroid cancer.