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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Update on pediatric psoriasis
1Department of Dermatology, 1090 Amsterdam Ave, Ste 11D, New York, NY 10025, USA. nsilverb@chpnet.org.
Insights
Pediatric psoriasis is linked to metabolic syndrome, including obesity and high blood pressure. Recent research highlights a generalized inflammatory nature, emphasizing lifestyle changes and weight control for managing this chronic skin condition.
Area of Science:
- Dermatology
- Pediatrics
- Metabolic Health
Background:
- Pediatric psoriasis, a chronic inflammatory skin condition, constitutes about one-third of all psoriasis cases.
- Emerging evidence indicates pediatric psoriasis shares similarities with adult psoriasis, being associated with a generalized inflammatory diathesis.
Purpose of the Study:
- To review recent studies (last 2 years) on pediatric psoriasis.
- To highlight the connection between pediatric psoriasis and metabolic syndrome components.
Main Methods:
- Literature review of studies published within the last two years.
- Focus on research pertinent to pediatric psoriasis and its systemic associations.
Main Results:
- Pediatric psoriasis is increasingly recognized as part of a broader inflammatory condition.
- Associated metabolic syndrome factors include obesity, hypertriglyceridemia, hypertension, and insulin resistance.
Conclusions:
- A shift in understanding pediatric psoriasis towards a systemic inflammatory disorder is occurring.
- Management strategies now emphasize lifestyle modifications, weight control, and systemic therapies alongside dermatological treatment.
Abstract:
Pediatric psoriasis accounts for approximately one-third of all cases of psoriasis. Although pediatric psoriasis was always understood to be a chronic inflammatory dermatosis, recent data suggest that pediatric psoriasis, similar to its adult equivalent, is part of a generalized inflammatory diathesis associated with metabolic syndrome, including obesity/overweight status, hypertriglyceridemia, high blood pressure, and insulin resistance. Given the recent proliferation of data demonstrating the generalized inflammatory nature of psoriasis, a new emphasis on adopting a healthier lifestyle and weight control as well as systemic therapies has emerged in the literature. This article briefly reviews selected studies published in the last 2 years that are pertinent to pediatric psoriasis.
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