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Intra-abdominal pressure correlates with extracellular water content
Wojciech Dąbrowski1, Edyta Kotlinska-Hasiec1, Andrzej Jaroszynski2
1Department of Anesthesiology and Intensive Therapy Medical University of Lublin, Lublin, Poland.
Plos One
|April 8, 2015
Summary
Intra-abdominal pressure (IAP) strongly correlates with extracellular water (ECW) and volume excess (VE). This finding is crucial for understanding fluid shifts in critically ill and surgical patients, aiding in risk assessment and management.
Area of Science:
- Critical Care Medicine
- Nephrology
- Surgical Physiology
Background:
- Secondary increases in intra-abdominal pressure (IAP) are linked to conditions like sepsis and massive fluid resuscitation.
- These conditions elevate extravascular water content, impacting physiological parameters.
- Understanding the relationship between IAP and body water is essential for patient management.
Purpose of the Study:
- To investigate the correlation between intra-abdominal pressure (IAP) and various body water volume measurements.
- To determine if body water volume parameters can predict increased IAP.
Main Methods:
- Adult patients with sepsis/septic shock and AKI, or undergoing elective surgery, were enrolled.
- Intra-abdominal pressure (IAP) measured via urinary bladder.
- Total body water (TBW), extracellular water (ECW), and volume excess (VE) assessed using whole-body bioimpedance.
Main Results:
- A strong correlation was observed between IAP and ECW, and IAP and VE across all participants.
- In critically ill patients, IAP correlated with ECW and VE.
- ROC analysis indicated ECW and VE as potential discriminative parameters for elevated IAP risk.
Conclusions:
- Intra-abdominal pressure (IAP) demonstrates a strong correlation with extracellular water (ECW).
- Extracellular water (ECW) and volume excess (VE) may serve as indicators for increased IAP.
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