Shed NKG2D ligand boosts NK cell immunity
Emilie Narni-Mancinelli1, Eric Vivier2
11] Centre d'Immunologie de Marseille-Luminy, UM2 Aix-Marseille Université, Marseille, France [2] INSERM U1104, Marseille, France [3] CNRS UMR7280, Marseille, France.
Cell Research
|April 8, 2015
Abstract:
Ligands for natural killer (NK) cell activating receptors can be released from tumor cells and are believed to promote tumor growth by acting as decoys for effector lymphocytes. In a recent paper published in Science, Deng et al. report another scenario in which a shed form of the MULT1 mouse NKG2D ligand boosts NK cell functions.
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