[A new nomenclature for natural killer cells]

Recent advances in single-cell transcriptomics have profoundly renewed our understanding of immune cells. They have enabled us to better characterize the heterogeneity of Natural Killer (NK) cells and establish a classification that integrates all their characteristics. These approaches have also shed light on the behavior of NK cells infiltrating the tumor microenvironment, the mechanisms of their dysfunction, and the limits of their antitumor activity. Finally, they are essential for understanding the mechanisms of action of new therapies targeting NK cells.