Related Experiment Video

Updated: Apr 15, 2026

Author Spotlight: Advancing Biomedical Research Through Single Cell Analysis
07:59

Author Spotlight: Advancing Biomedical Research Through Single Cell Analysis

Published on: December 22, 2023

3.9K

SNES: single nucleus exome sequencing

Marco L Leung, Yong Wang, Jill Waters

    Genome Biology
    |April 9, 2015
    PubMed

    More Related Videos

    Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-nucleus RNA Sequencing06:38

    Isolation of Adult Spinal Cord Nuclei for Massively Parallel Single-nucleus RNA Sequencing

    Published on: October 12, 2018

    20.0K
    Nuclei Isolation from Whole Tissue using a Detergent and Enzyme-Free Method07:00

    Nuclei Isolation from Whole Tissue using a Detergent and Enzyme-Free Method

    Published on: June 24, 2020

    27.3K

    Related Concept Videos

    RNA-seq03:21

    RNA-seq

    RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
    Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while...
    12.7K
    Next-generation Sequencing03:00

    Next-generation Sequencing

    The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
    Next-Generation Sequencing Methods
    Although all next-generation methods use different technologies, they all share a set of standard features....
    101.9K
    Sanger Sequencing01:57

    Sanger Sequencing

    DNA sequencing is a fundamental technique that is routinely used in the biological sciences. This method can be applied to a range of questions at different scales - from the sequencing of a cloned DNA fragment or the study of a mutation in a gene up to whole-genome sequencing. However, despite the widespread use of sequencing today, it was not until 1977 that Fredrick Sanger and his collaborators developed the chain-termination method to decode DNA sequences. It relies on the separation of a...
    780.2K
    Single Nucleotide Polymorphisms-SNPs01:05

    Single Nucleotide Polymorphisms-SNPs

    A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
    20.1K