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Updated: Apr 15, 2026

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Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
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[Iatrogenic Keratectasia: A Review]
1Klinik für Augenheilkunde, St.-Johannes-Hospital, Dortmund.
Summary
Iatrogenic corneal ectasia, a feared complication after laser eye surgery, can cause vision loss. Early detection and risk factor management, including corneal cross-linking, are crucial for preventing severe visual impairment.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Refractive Surgery
Context:
- Iatrogenic corneal ectasia is a rare but serious complication following corneal laser surgery.
- It can manifest weeks to years after procedures like LASIK, PRK, and other refractive surgeries.
- Reported incidence rates vary, ranging from 0.04% to 2.8%.
Purpose:
- To review the characteristics, risk factors, and management of iatrogenic corneal ectasia.
- To highlight the progressive nature of the condition and its impact on visual acuity.
- To discuss current treatment options, including corneal cross-linking and surgical interventions.
Summary:
- Corneal ectasia presents with progressive myopia, irregular astigmatism, and significant visual disturbances.
- Key risk factors include thin corneas (<500 µm), shallow residual stromal bed (<300 µm), high myopia (>8 D), young age (<25 years), and a history of allergies or keratoconus.
- Treatment involves corneal cross-linking with riboflavin/UVA light; severe cases may require corneal transplantation.
Impact:
- Understanding risk factors and early signs of corneal ectasia is vital for patient safety in refractive surgery.
- Prompt diagnosis and treatment, such as corneal cross-linking, can halt disease progression and preserve vision.
- This review provides essential information for ophthalmologists managing patients at risk for or presenting with post-refractive surgery ectasia.
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