Related Experiment Video
Updated: Apr 15, 2026

Refined Murine Model of Idiopathic Pulmonary Fibrosis
Published on: June 17, 2025
Idiopathic pleuroparenchymal fibroelastosis: a rare but increasingly recognized entity
M T Redondo1, N Melo1, P C Mota2
1Department of Pneumology, Centro Hospitalar de São João, Portugal.
Abstract:
Idiopathic pleuroparenchymal fibroelastosis (IPPFE) is a recently described rare entity, characterized by pleural and subpleural parenchymal fibrosis and elastosis mainly in the upper lobes. The etiology and pathophysiology are unknown. The prognosis is poor, with no effective therapies other than lung transplantation. IPPFE should be properly identified so that it can be approached correctly. This report describes two clinical cases with clinical imaging and histological features compatible with IPPFE.
Related Concept Videos
Pleural Effusion I: Introduction
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
Pleural Effusion II: Symptoms and Management
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
Pleural Disorders: Types and Brief Description
Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Inflammation
Pleura of the Lungs
Cardiomyopathy IV: Restrictive Cardiomyopathy

