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Updated: Apr 15, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Transaortic Transcatheter Aortic Valve Implantation as a Second Choice over the Transapical Access
J Ropponen1, T Vainikka1, J Sinisalo2
1Department of Cardiac Surgery, Heart and Lung Center, Helsinki University Hospital, Helsinki, Finland.
Transaortic transcatheter aortic valve implantation (TAVI) is a viable alternative to the transapical approach. This TAVI method offers comparable outcomes, even in higher-risk patients, and is suitable when transfemoral access is not possible.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Medical Devices
Background:
- Transcatheter aortic valve implantation (TAVI) is a crucial procedure for aortic stenosis.
- Non-transfemoral TAVI approaches, including transaortic and transapical, are used for patients with unsuitable iliofemoral anatomy.
- Comparing these access routes is essential for optimizing patient outcomes.
Purpose of the Study:
- To compare the procedural success, 30-day outcomes, and up to 2-year survival of transaortic TAVI versus transapical TAVI.
- To evaluate the safety and efficacy of the SAPIEN valve via transaortic access.
Main Methods:
- A retrospective analysis of 100 non-transfemoral TAVI patients.
- 36 patients underwent transaortic access, and 64 underwent transapical access.
- Comparison of baseline characteristics, procedural success, perioperative complications, and survival rates.
Main Results:
- Technical success rates were 100% for transaortic and 95.2% for transapical (p=NS).
- The transaortic group experienced fewer perioperative hemodynamic issues (2.8% vs 18.8%, p=0.023) and shorter hospital stays (7 vs 8 days, p=0.018).
- 30-day and 1-year survival rates were comparable between groups (p=NS).
Conclusions:
- Transaortic TAVI is a valuable alternative to the transapical approach, offering comparable clinical outcomes.
- This method is particularly useful for patients with prohibitive iliofemoral anatomy for transfemoral access.
- Transaortic TAVI demonstrates safety and efficacy, even in a higher-risk patient cohort.
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