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Published on: June 20, 2018
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Prosthetics for nasal perforations: a systematic review and meta-analysis
Robert J Taylor1, David A Sherris2
1Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA taylorob@musc.edu.
Summary
Nasal septal prosthetics offer a viable treatment for nasal septal perforations, especially for patients unsuitable for surgery. This review found a 65% success rate, indicating prosthetics are effective and safe for managing nasal septal perforations.
Area of Science:
- Otolaryngology
- Medical Devices
- Surgical Innovation
Background:
- Nasoseptal perforations can significantly impact quality of life.
- Prosthetic devices present a non-surgical treatment option for nasoseptal perforations.
- This approach is particularly relevant for patients with systemic diseases or those who are poor surgical candidates.
Purpose of the Study:
- To systematically review and critically appraise existing literature on nasoseptal prosthetics.
- To evaluate the success rate and safety profile of prosthetic treatment for nasoseptal perforations.
- To establish evidence-based guidelines for the clinical application of nasoseptal prosthetics.
Main Methods:
- Systematic literature search of Cochrane Controlled Trials Register, EMBASE, PubMed, and Web of Science (1965-2013).
- Inclusion criteria: primary data on human nasoseptal perforation treatment using prosthetics.
- Quantitative meta-analysis of low-risk-of-bias studies (6 studies, 297 patients).
Main Results:
- A total of 706 cases were identified from 23 case series and 5 case reports.
- All studies provided Level 4 evidence with a Grade C recommendation.
- Meta-analysis revealed an overall prosthetic success rate of 65%.
Conclusions:
- The current literature supports the efficacy and safety of nasoseptal prosthetics for perforation treatment.
- Prosthetic devices demonstrate favorable success rates with a low incidence of complications.
- Further research is warranted to refine treatment guidelines and explore optimal prosthetic use.
