Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Anionic Chain-Growth Polymerization: Overview01:20

Anionic Chain-Growth Polymerization: Overview

2.8K
The polymerization process that involves carbanion as an intermediate is called anionic polymerization. It is also a type of addition or chain-growth polymerization. Anionic polymerization gets initiated by a strong nucleophile such as an organolithium or a Grignard reagent. The most commonly used initiator for anionic polymerization is butyl lithium. Monomers involved in anionic polymerization must possess a vinyl group bonded to one or two electron-withdrawing groups. For instance,...
2.8K
Cationic Chain-Growth Polymerization: Mechanism00:57

Cationic Chain-Growth Polymerization: Mechanism

3.1K
The cationic polymerization mechanism consists of three steps: initiation, propagation, and termination. In the initiation step of the polymerization process, the π bond of a monomer gets protonated by the Lewis acid catalyst, which is formed from boron trifluoride and water. The protonation of the π bond generates a carbocation stabilized by the electron‐donating group. In the propagation step, the π bond of the second monomer acts as a nucleophile and attacks the...
3.1K
Anionic Chain-Growth Polymerization: Mechanism01:04

Anionic Chain-Growth Polymerization: Mechanism

2.6K
The mechanism for anionic chain-growth polymerization involves initiation, propagation, and termination steps. In the initiation step, a nucleophilic anion, such as butyl lithium, initiates the polymerization process by attacking the π bond of the vinylic monomer. As a result, a carbanion, stabilized by the electron‐withdrawing group, is generated. The resulting carbanion acts as a Michael donor in the propagation step and attacks the second vinylic monomer, which acts as a Michael...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retrograde migration of a fractured plastic biliary stent fragment after percutaneous displacement into the bowel in a patient with hepaticojejunostomy requiring repeat percutaneous retrieval.

Radiology case reports·2026
Same author

Bioactive Hydrogels with D-Amino Acid RGD Mimics: A Therapeutic Strategy for Expeditious Infected Wound Closure.

Advanced healthcare materials·2026
Same author

Accidental Bowel Transgression/Close Proximity During Percutaneous Microwave Ablation of Liver Tumors: A Retrospective Case Series.

Journal of clinical medicine·2026
Same author

A novel molecule inhibits SARS-CoV-2 RBD binding to the ACE2 receptor, blocks viral entry and exhibits antiviral activity in a murine model.

Archives of virology·2026
Same author

Early immunogenic response to intradermal, subcutaneous, and intramuscular rabies vaccination in cattle and buffaloes: a field study.

Tropical animal health and production·2026
Same author

Structural and Biochemical Insights into Cotton 5-Enolpyruvylshikimate-3-Phosphate Synthase: Toward Inhibitor Design and Glyphosate Resistance.

Journal of agricultural and food chemistry·2025

Related Experiment Video

Updated: Apr 15, 2026

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
10:43

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

9.6K

Cationic polymers and their self-assembly for antibacterial applications.

Smriti Rekha Deka, Ashwani Kumar Sharma, Pradee Kumar1

  • 1Nucleic Acids Research Laboratory, CSIR-Institute of Genomics and Integrative Biology, Mall Road, Delhi -110 007, India. pkumar@igib.res.in.

Current Topics in Medicinal Chemistry
|April 11, 2015
PubMed
Summary

Amphiphilic cationic polymers self-assemble to disrupt bacterial cell walls, offering a novel solution for drug-resistant infections. These advanced polymers show potent antibacterial activity with low toxicity.

More Related Videos

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

8.4K
Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
10:53

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions

Published on: October 10, 2016

14.7K

Related Experiment Videos

Last Updated: Apr 15, 2026

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices
10:43

High-throughput Identification of Bacteria Repellent Polymers for Medical Devices

Published on: November 5, 2016

9.6K
Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives
09:22

Self-assembling Morphologies Obtained from Helical Polycarbodiimide Copolymers and Their Triazole Derivatives

Published on: February 7, 2017

8.4K
Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
10:53

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions

Published on: October 10, 2016

14.7K

Area of Science:

  • Polymer Chemistry
  • Microbiology
  • Biotechnology

Background:

  • Antibiotic resistance is a growing global health threat.
  • Cationic polymers and peptide oligomers are key antibacterial macromolecules.
  • Developing novel antibacterial agents is crucial.

Purpose of the Study:

  • To review advances in amphiphilic cationic polymers as antibacterial agents.
  • To discuss their self-assembly and mechanism of action.
  • To highlight their potential against drug-resistant bacteria.

Main Methods:

  • Focus on amphiphilic cationic polymers, including natural and synthetic types.
  • Discuss polymer self-assembly in aqueous conditions.
  • Analyze interactions with bacterial cell walls and membranes.

Main Results:

  • Amphiphilic cationic polymers effectively interact with bacterial cell surfaces.
  • Disruption of transmembrane potential leads to cell death.
  • Modified analogs demonstrate low hemolytic activity and broad-spectrum antibacterial efficacy.

Conclusions:

  • Amphiphilic cationic polymers represent a promising platform for combating resistant microbial infections.
  • Their ability to disrupt bacterial cell walls offers a new therapeutic strategy.
  • Further development holds potential for novel disinfectants and biocides.